Of the four nations in the group, only the Indomitable Lions and the Elephants have taken part at the finals before, with the former appearing seven times, while the latter have participated on three occasions (2006, 2010 and 2014).
Cameroon have the most appearances at the global showpiece, playing in seven tournaments (1982, 1990, 1994, 1998, 2002, 2010 and 2014).
Furthermore, the Indomitable Lions’ 23 games at the World Cup is the most any African side has played in at the finals.
They reached the quarter-final in 1990, another African record, which they share with Senegal (2002) and Ghana (2010).
40 teams will partake in the draw on Tuesday evening, which will see 10 groups comprising four teams each.
The winners of every group will then advance to the third and final round of the qualifiers, with each team to play the other home and away.
The aggregate five winners at the conclusion of the fixtures will then represent Africa at the global showpiece in Qatar.
Having missed the competition in Russia in 2018, Cameroon will seek to take part in the tournament to be held in three years.